In a mixing bowl, combine ground beef, breadcrumbs, beaten egg, garlic powder, onion powder, salt, and black pepper. Mix well.
Form the mixture into meatballs, about 1 inch in diameter.
Place the meatballs in the air fryer basket in a single layer. Cook for 10-15 minutes, shaking the basket halfway through, until the meatballs are cooked through and golden brown.
Serve hot with your favorite dipping sauce or pasta.